Sequence Variation in the Herpes Simplex Virus US1 Ocular Virulence Determinant
نویسندگان
چکیده
منابع مشابه
Sequence variation in the herpes simplex virus U(S)1 ocular virulence determinant.
PURPOSE The herpes simplex virus type 1 (HSV-1) U(S)1 gene encodes host-range and ocular virulence determinants. Mutations in U(S)1 affecting virulence are known in strain OD4, but the genomic variation across several strains is not known. The goal was to determine the degree of sequence variation in the gene from several ocular HSV isolates. METHODS The U(S)1 gene from six ocular HSV-1 isola...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2011
ISSN: 1552-5783
DOI: 10.1167/iovs.10-7032